When Michele Donato Giacullo was born on 10 January 1842, in Sessano, Molise, Italy, his father, Antonio Giacullo, was 37 and his mother, Nunzia Petrollini, was 30. He married Nunzia Antonia Valerio on 20 September 1871, in Sessano, Molise, Italy. They were the parents of at least 3 sons and 1 daughter. He died on 4 December 1892, in Sessano, Campobasso, Molise, Italy, at the age of 50, and was buried in Sessano, Campobasso, Molise, Italy.